Abstract:

Protein is the main nutrition of human beings and the main substance of human body. 40% of the living human body is protein. If the human body is dehydrated, 70% of the dry weight of human body is composed of protein. The lack of human protein is directly related to and affects human health, immunity and growth and development. Therefore, human protein is the bridge, source and life of human life This is the foundation.

Where does human protein come from? It comes from the food protein that people usually eat. After the food protein enters the human body, it needs the enzyme in the food protein: such as amylase, and the endopeptidase of the human body itself: such as digestive enzyme, pepsin, trypsin, as well as the stomach acid, bile and other substances of the human body to catalyze and decompose the food protein, so that it can be absorbed and utilized by the human body 。 In the past, science believed that human body absorbed proteins mainly in the form of amino acids. In the past 20 years, scientific research found that human body absorbed proteins mainly in the form of small peptides, which can enter cells directly and be absorbed earlier and earlier than amino acids. Amino acids can only be used by human body after the liver synthesizes small peptides.

In modern society, protein nutrition products are very rich. The supermarket shelves are colorful, cheap and easy to get, but the people who account for a large proportion are lack of protein nutrition. What's the reason?

After scientific research, it is found that there are two main reasons. One is the lack of enzyme in modern food. Chemical fertilizer and pesticide are the main culprit of taking enzyme from food. The lack of enzymes in food makes people lose the ability to digest and decompose macromolecular proteins. Second, the enzyme of human body also loses its activity. The chemical fertilizer and pesticide residues in food are "Robbers" who take away the enzyme activity of human body. We compare the enzyme in food and the enzyme in human body as an enzyme scissors. If the enzyme is inactivated, it means that the enzyme scissors are blunt. If the macromolecular protein cannot be decomposed and digested, the macromolecular protein will not become small peptide and amino acid. Then the main form of protein absorption in human body: peptide and amino acid, there is nothing to absorb, so this is the great abundance of modern protein Rich, but the main reason for the lack of protein in the human body.

The lack of protein in human body can cause more than 100 kinds of problems caused by the lack of protein nutrition. Therefore, to solve the sub-health and unhealthy problems, we must solve its "root".Not only that, for drug blind, medical blind and health blind people, they think that the lack of protein is to desperately supplement high protein, and the result is just the opposite. The body has a variety of problems, such as high blood pressure, hyperlipidemia, hyperglycemia, tumor, etc. Instead of nourishing the protein, the high protein and macromolecular protein that we eat cannot be degraded due to the lack of enzyme and human body enzyme in the protein food, which makes macromolecular protein accumulate in the body due to the non degradation and poor external excretion ability, which sticks to various organs of the intestine and five viscera and six Fu organs, sticks to blood vessels, and turns into toxin and cannot be discharged.

In this way, all kinds of organs and blood vessels of the whole digestive system will accelerate aging, and people's life expectancy will be greatly shortened, especially many people who have kidney disease will go to the hospital for dialysis. Therefore, to eat macromolecular protein, in the absence of enzyme in the human body can not be digested into small peptides and amino acids, is to eat a poison.

In order to solve the problem that protein nutrition is extremely rich but the human body lacks protein nutrition, Zou Yuandong led his scientific research team to focus on this problem 20 years ago. He led the scientific research team to study in the professional branch of Shanghai Academy of Sciences, invited retired experts to the company for discussion, took out an oral liquid workshop as an experimental factory in his charge A scientific experiment simulating the degradation and digestion of protein by human body to solve the problem that protein and food are not lacking but protein and nutrition are lacking in human body was started.

Under the expert's advice, they first used raw egg as substrate, broke an egg by hand, then poured it into the enzymolysis tank, and then used the enzyme preparation of animals for catalysis,Some people smell a pungent smell on the streets of the city. After the investigation of the relevant departments of the city, it turns out that the smell comes from this experimental factory. In numerous experiments, Zou Yuandong thought that if raw eggs were used as the catalytic substrate, it would be too primitive and backward, so they used the semi-finished egg powder as the substrate, or animal enzyme as the enzymatic hydrolysis catalyst.

The catalytic product was more amino acids and less peptides, and still had bitter and fishy taste, but it was a big step forward compared with the product with raw eggs as the substrate. Zou Yuandong and His technical team continued to study and found that the peptide bond of the substrate egg powder has been opened in the process of making egg powder, so it can no longer be catalyzed by the strong animal protease, which is equivalent to killing chickens and using the ox knife.

He wanted to speed up, but could not reach it. So Zou Yuandong bought hundreds of books and papers on enzyme preparation, and also bought several sacks from the food science journal To go back to the backlog of publications, with dozens of food enzymes in the laboratory for a small test, and finally found the latest enzyme technology achievements, he learned that several kinds of aromatic fruit protease have different characteristics, according to their characteristics after the scientific formula, the formation of mutual action, take advantage of the short, gradient catalysis, so their experiment has been successful.

After they put the substrate and the formula of the enzyme preparation into the enzymolysis tank, they have achieved great success. The trial products have been tested by the testing center of Jiangnan University, an authoritative testing institution in China, and have made breakthroughs in many aspects. First, the molecular weight is distributed below 1000 daltons, second, the mixture of peptide and amino acid, and the peptide content is more than 90%,The third is that the small peptide is composed of two to six amino acids. The fourth is that the peptide contained has a strong activity and diversity. The fifth is that the peptide contained has an important biological function. The sixth is that the peptide contained has a green attribute. According to the novelty search report of the national science and technology information novelty search agency, it fills in the gaps in related industries.

The overseas edition of people's daily solemnly announced to the world that China has developed a small molecule active peptide produced by enzymatic method. The news shocked the world, and then Guangming Daily, the authoritative media of science, education and culture in China, published a long newsletter of "Zou Yuandong and the enzymatic polypeptides he founded" on the front page, then published Zou Yuandong's invention and creation of enzymatic polypeptides in three and a half editions of "Zou Yuandong from the head of the enterprise to the scientist" and "Zou Yuandong from the scientist to the popular science writer";

People's daily, people's Liberation Army Daily, science and technology daily, China medicine daily, China Senior Citizen Daily and China food daily all published Zou Yuandong's self innovation of enzymatic polypeptide in full page and half page. At the same time, Zou Yuandong was received by the principal of the Ministry of science and technology of China and the president of the Chinese Academy of Sciences and the Chinese Academy of engineering at that time. Therefore, Zou Yuandong was awarded the title of The Chinese inventors Forum jointly held by the Ministry of science and technology of the people's Republic of China, the State Intellectual Property Office of the people's Republic of China and the China Invention Association supported by the China Association for science and technology won the "invention and entrepreneurship Award", "invention and entrepreneurship award · people award", was awarded the honorary title of "contemporary inventor", the "United Nations peace messenger" awarded by the United Nations, and the "national excellent entrepreneur" awarded by the China Enterprise Federation,For this reason, Zou Yuandong was elected vice president of China Invention Association.

Under the leadership of China Invention Association, Zou Yuandong's series of major invention achievements of enzymatic peptide represented the national team and successively participated in Germany, France, Britain, Switzerland, Thailand, Iran and Russia, winning 23 gold awards, 11 silver awards and 5 Bronze awards. One of the results of enzymatic polypeptide series has obtained American patent and Japanese patent。

The technology of peptide production led by Zou Yuandong is quite different from the technology of following the trend in the market. The follow-up products on the market are basically based on the "fine chemical industry, production of amino acids" to produce peptides, while jiushengtang uses "biological enzyme catalytic protein" to obtain small molecular peptides. The peptide produced by the method of "fine chemical engineering and amino acid production" accounts for 90% of amino acid and only 5-10% of small peptide. Therefore, it can not be called peptide. Its essence is amino acid. The peptide produced by this technology has no activity and can not form stable function, that is to say, it basically has no function and efficacy. The peptide obtained by jiushengtang with "biological enzyme catalysis protein" accounts for more than 90% of the peptide content, and only 5-10% of the amino acid content. The peptide contained in jiushengtang has strong activity and diversity, can form stable function, and has high biological potency.

Nowadays, there are four peptides with national approval in China, and jiushengtang has three. Consumers take peptides without national approval at will (i.e. little blue hat), which is tantamount to "joking" about their life and health. Jiushengtang, led by Zou Yuandong, not only pioneered the production of small molecular active polypeptides by enzymatic method,Moreover, it has subverted the traditional methods and technology of peptide production, and the produced peptide has no bitterness, fishy smell and odor, and solved the major technical problems of traditional peptide production, such as bitterness, fishy smell and odor, which need to be removed. Zou Yuandong described the technological innovation of peptide production as "a model simulating the degradation of protein by human body".

The principle and conditions of protein digestion in human body are carried out in vitro. The temperature, pH value of protein digestion in human body and the amount of motion of human body during protein digestion are changed into the rotation speed of enzymatic hydrolysis machine by using the factory's machine equipment and biological enzyme formula, and the same peptide produced by protein digestion in human body is obtained. The peptide produced by this method has strong activity, diversity and importance Its biological function is good for consumers to take and has a high return rate.

The oral liquid of Sanjiu protein peptide, a key product of enzymatic peptide produced by jiushengtang under the leadership of Zou Yuandong, has become a new upstart in China's health care market. It is awarded as "China's top health care product", i.e. "high-tech product", listed as "National Torch Program", "National 863" project, "National Science and technology based small and medium-sized enterprise innovation fund support" project and "China Zou Yuandong, the inventor of the joint conference of mayors of five southern provinces and two cities, was received by 51 party and state leaders and 420 provincial and ministerial leaders.

Sanjiu protein peptide oral liquid is one of the earliest products approved by peptide health care products in China, with a return rate of 79.5%, benefiting millions of people and gaining health.All the old people who have taken it regard it as a "magic weapon of protection". When people grow old, their digestive and absorption systems begin to degenerate, and their ability to acquire protein is greatly weakened. In addition, chemical fertilizer and pesticide residues take away the enzyme in food and inactivate the enzyme in human body, which makes the ability of modern old people to acquire protein even worse.

When the old people lack protein, they are weak and sickly, have low immune function, and all kinds of physical discomfort symptoms occur sometimes. Can they take it or not Protein peptides that need to be digested and absorbed directly supplement protein nutrition in the form of small peptides. When the human body supplements the protein, the problems caused by the lack of protein nutrition will be alleviated and disappeared.

The human body is composed of more than 60 trillion cells. The main component of cells is protein. The activity of cells and the main active substance of human body are in the form of small peptide. The active substance of human body is life. After taking small peptide, it can directly enter human cells, synthesize cells, produce cells, repair damaged cells, regulate the function of cells, and affect the synthesis of human specific proteins through DNA transcription. After the small peptide enters the human body, it quickly merges with the cell membrane, building a protective wall for the cells, making it difficult for all kinds of bad cells to enter, and preventing the invasion of all kinds of bad cells.

Immunity is an eternal theme of human beings. Peptide immunity is the top grade in immunity. Most of the traditional peptide immunity agents are obtained from the gland tissues of animals. There is a risk of rejection when human beings use them. As a new peptide immunity agent, the Sanjiu protein peptide has become a new favorite in peptide immunity agents.

The peptide in Sanjiu protein peptide is an oral product from food protein. No There will be exclusion,Compared with the traditional peptide immune agents, it is superior to the traditional peptide immune agents in use occasions, use conditions, users, use risks, etc. Sanjiu protein peptide has been approved by the state to adapt to the population, which includes the patients with multiple diseases, low immune function, radiotherapy and chemotherapy, and regular exposure to radiation.

Zou Yuandong explained that when the country approved three nine protein peptides as four types of adaptive population, he said: "the weak and multiple patients refer to the degenerative and aging problems caused by the lack of protein nutrition.

By supplementing human protein in the form of small peptides, the body will be strong, the spirit and energy will be sufficient, and many problems caused by the lack of protein will be alleviated." When talking about the second group of people with low immune function, Zou Yuandong said: "low immune function means that the cells lose the protective membrane and protective wall, which makes the cell resistance lose and weaken, and the bad cells will collide in the human body, and go straight to enter. When the bad cells enter the human body, they first need to fuse with the human cell membrane, and then their genetic material will enter the nucleus, when the cell sense After infection, it will become inflamed, then infect the surrounding cells, and the human body will have discomfort.

If the peptide absorbed by the human body first fuses with the cell membrane to form an antibody, the bad cells will not enter the cells that cannot be fused by the small peptide, and can only flow in the blood for four hours, and will also self apoptosis and be discharged from the body by the human excretory system. " Zou Yuandong, who is the third suitable population for radiotherapy and chemotherapy approved by the state, said: "when people are in radiotherapy and chemotherapy, good cells and bad cells are killed together. When the good cells are killed to the critical limit, people begin to eat nutrition to increase leukocytes,But in the past, white blood cells and bad cells were rising, and bad cells rose faster than good cells, and finally took away human life.

Taking Sanjiu protein peptide oral liquid, the situation has changed. Small peptide can help patients completely and stably regulate the immune function and stimulate the phagocytosis of macrophages in immune cells. In this way, people can make good cells rise fast and bad cells rise slowly in the course of radiotherapy and chemotherapy, and finally cooperate with radiotherapy and chemotherapy to subdue bad cells. " When talking about the fourth adaptive population approved by the state for Trinity protein peptide, who often contact with radiographers, said: "for example, the medical and nursing staff in the radiology department of the hospital, who often contact with computer radiation, power radiation, household appliance radiation, who often use modern communication tools, new decoration family, smelting factory workers, mining workers, can supplement eggs in the form of small peptide White matter repair cells, strong anti radiation, to maintain their own health

Zou Yuandong's "enzymatic peptide" major invention and products will benefit mankind!

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Chengdu Shengnuo Biotechnology Co., Ltd. has "Chengdu polypeptide drug engineering technology research center" in Chengdu, mainly engaged in polypeptide, polypeptide drug and beauty peptide research. Our zero defect has passed the FDA certification, and now it has become the first-class professional peptide drug and product development, technology transfer, technical service and peptide drug industry in the scale production and export of China's parks.