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Source: National Health and Health Commission

- ### Q: what is the novel coronavirus asymptomatic infection control requirement in China?

- ### Q: What is the way to find asymptomatic infection? So far, how many asymptomatic infections have been found in China?

- ### Q: Is asymptomatic infection contagious? A kind of

- ### Q: How to do a good job in risk assessment and prevention of asymptomatic infection?

- ### Q: How to prevent and control asymptomatic infection?

- ### Q: How to do personal protection well?

A: Asymptomatic infection of new coronavirus (hereinafter referred to as asymptomatic infection) refers to those who have no relevant clinical symptoms, such as fever, cough, pharyngeal pain and other symptoms and signs that can be self perceived or clinically recognized, but whose pathogenic test of new coronavirus on respiratory tract and other specimens is positive.

Asymptomatic infection can be divided into two situations: one is that the infected person's nucleic acid test is positive, after 14 days of incubation period observation, there are no symptoms and signs that can be self perceived or clinically recognized, and it is always asymptomatic infection;

the other is that the infected person's nucleic acid test is positive, and there are no symptoms and signs that can be self perceived or clinically recognized when sampling, but then there is a certain clinical table Now, it is in the incubation period of "asymptomatic infection" state.

### Q: what is the novel coronavirus asymptomatic infection control requirement in China?

Novel coronavirus asymptomatic infection was introduced into the prevention and control management of the new crown virus infection prevention and control program (Third Edition) released by the A: national health and Health Committee in January 28th. In the subsequent revision process, specific and specific requirements were made for the reporting and management of asymptomatic infections.

If asymptomatic infection is found in all kinds of medical and health institutions at all levels, network direct report shall be made within 2 hours. After receiving the report of asymptomatic infected persons, the county (District) disease control institution shall complete the case investigation within 24 hours, register the close contacts in time, and report the case investigation form or investigation report through the infectious disease report management information system in time.

The asymptomatic patients should be isolated for 14 days. In principle, the patients who have been isolated for 14 days and whose nucleic acid test of two consecutive samples is negative (the sampling time should be at least 24 hours apart) can be removed from the isolation.

If the nucleic acid test is still positive, the patients should continue to be isolated for medical observation. In case of clinical manifestations during the period of isolation medical observation, they should be timely classified as confirmed cases for standardized treatment. Close contacts of asymptomatic patients also need 14 days of intensive isolation medical observation.

### Q: What is the way to find asymptomatic infection? So far, how many asymptomatic infections have been found in China?

Novel coronavirus pneumonia is the novel coronavirus pneumonia case. A: currently we actively detect asymptomatic infections through the following ways: first, active detection of the new type of coronavirus pneumonia cases during close medical contacts;

two, active detection in the investigation of the cluster epidemic; three, active detection of the exposed population in the process of tracing the source of the new coronavirus pneumonia; four, some of the territory.

Active history of novel coronavirus pneumonia cases was carried out in the areas of continuous travel history and residence history.

As of 24:00 on March 30, 2020, there were 1541 asymptomatic infections under medical observation, of which 205 were imported from abroad.

### Q: Is asymptomatic infection contagious? A kind of

A: According to the monitoring data of close contacts carried out by the state and some provinces, the close contacts of asymptomatic infected people have the second generation of cases. In the epidemiological investigation, it is found that individual clustered epidemic situation caused by asymptomatic infected people.

A small sample size study shows that the viral load in the respiratory samples of asymptomatic infected people is not much different from that of the confirmed cases. According to the current monitoring and research, asymptomatic patients are infectious, but the length of the infection period, the intensity of the infection and the mode of transmission need further scientific research.

Some experts believe that in view of the fact that the respiratory tract samples of asymptomatic patients can detect pathogenic nucleic acids, but due to the absence of clinical symptoms such as coughing and sneezing, the chance of pathogen excretion in vitro to cause transmission is relatively less than that of confirmed cases.

### Q: How to do a good job in risk assessment and prevention of asymptomatic infection?

A: There is a risk of transmission in asymptomatic patients. One is the concealment of communication. As asymptomatic infection has no obvious symptoms and signs, it is difficult to be found in the population, and the transmission caused by it is also difficult to prevent.

The second is the subjectivity of symptoms. Patients with mild or atypical symptoms may think that they are not infected with the new coronavirus, do not take the initiative to visit medical institutions, and are difficult to be found in daily diagnosis and treatment work.

Third, the limitations of discovery. Due to the detection window period, it is difficult to find all asymptomatic infected persons by nucleic acid detection and serological detection. The existing asymptomatic infected persons are mainly found by active screening of close contacts of cases, investigation of infection source, investigation of clustering epidemic situation and active detection of personnel in high-risk areas, and some asymptomatic infected persons are difficult to be found.

Therefore, we should focus on the monitoring of asymptomatic patients, strengthen the screening efforts, and expand the detection scope to the close contacts, key areas and key populations of the cases and asymptomatic patients. Once asymptomatic infection is found, isolation and medical observation shall be carried out in strict accordance with the requirements of "four mornings", and isolation medical observation shall also be carried out for close contacts.

Because some asymptomatic infected people are always asymptomatic, it is impossible to find and isolate asymptomatic infected people as the leading measure in the actual prevention and control work.

Therefore, we will continue to focus on the timely detection of isolated patients, and do a good job in the management of close contacts. China's experience shows that timely detection and isolation of confirmed cases, and appropriate measures to reduce interpersonal contact, can basically block the spread of the epidemic.

### Q: How to prevent and control asymptomatic infection?

A: First, improve the prevention and control plan. We should promptly take a certain proportion of samples from key epidemic areas, carry out investigation and epidemiological analysis of asymptomatic infected people, improve prevention and control measures, revise and improve prevention and control programs and diagnosis and treatment programs, scientifically respond to the infection risks brought by asymptomatic infected people, and contain the possible spread of new epidemic.

Second, increase screening and monitoring. We will increase the screening efforts in a targeted way, and expand the detection scope to the close contacts, key areas and key populations of the found cases and asymptomatic infected people. In combination with the practice of returning to work and returning to school, strengthen the monitoring of key cities, key groups and key places, and find out the hidden dangers to the greatest extent. Prevent the cross-border import and export of the epidemic situation, and detect the nucleic acid of all the entry personnel. After finding asymptomatic infection, carry out epidemiological investigation in time, identify the source, and release information openly and transparently.

Third, strengthen management and treatment. Once asymptomatic infection is found, isolation and medical management shall be strictly centralized according to the requirements of "four early hours", and isolation medical observation shall be carried out for close contacts. In case of symptoms during isolation, they shall be immediately transferred to designated medical institutions for treatment.

Fourth, strengthen group prevention and control. Adhere to the combination of groups and specialties, increase the publicity of epidemic prevention knowledge, guide the public in scientific protection, carry out extensive training, and improve the prevention and control ability and level of grassroots disease control personnel, medical personnel and community workers. From April 1, the report, outcome and management of asymptomatic infected persons will be publicized in the epidemic notification to respond to social concerns in a timely manner.

### Q: How to do personal protection well?

A: the public should strengthen their awareness of self protection and health and civilization, strengthen environmental hygiene and personal hygiene protection, and develop healthy hand behaviors such as washing hands, wearing masks, paying attention to hand hygiene, one meter line, ventilation, cleaning and disinfection, dining separately, reducing the number of people to gather places and wearing scientific respirators when they are sick. We should carry out patriotic health campaign extensively, spread health knowledge to every family and individual, form good health habits and civilized, healthy, green and environmental lifestyle, and improve mental health and health literacy level in line with the concept of protecting ourselves as well as other people's health.

If there is no need to panic after the personal nucleic acid test is positive, it is necessary to actively cooperate with the medical and health institutions to do a good job in health monitoring and isolation medical observation, report the symptoms such as fever and cough in time, and receive standardized diagnosis and treatment from the medical institutions.

The novel coronavirus novel coronavirus pneumonia is a positive response to the National Health Protection Committee and the Chinese medicine bureau's notice on the issuance of a new diagnostic and therapeutic plan for severe coronavirus pneumonia (trial version second). The notice said: "for patients with severe new coronavirus pneumonia with low lymphocyte counts and low cellular immunity, it is recommended to consider thymosin alpha 1". Therefore, the donation of

by San Nuo biology is also needed by the epidemic situation.

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