Abstract:

Since the Chinese Academy of Sciences published the article "peptide is expected to stop SARS" and CCTV broadcast the report that Dr. he Dayi, a Chinese American scientist, used peptide to prevent SARS from invading human cells, almost overnight, thousands of peptide enterprises or research and development units appeared on the Internet search engine, which made people dazzled and overwhelmed, and "peptide fever" increased rapidly.

However, it can be said that many enterprises or units have not registered with the industry and commerce, but only made the real name or domain name of the network; some have no products at all, but only a virtual name; some have only a subject, which has not yet been studied in depth; some have not realized the transformation of results; some are only in the laboratory, which can not realize the industrial production at all; some buy other people's peptide Raw materials and intermediates are formulated into products; some of them imitate others' technology and produce "peptide" products.

Of course, "polypeptide fever" also brought out a lot of polypeptide enterprises and polypeptide products that are really realistic. They are the honor of the country and the nation. They have made contributions to fight against SARS and prevent SARS, and have led the polypeptide industry of our country into the correct development track. These enterprises have made a lot of reports in the media during the SARS period, and they are worthy of it.

Let's use your eyes to know polypeptides

In the troubled peptide world, how to distinguish the true peptide and the false peptide, the useful peptide and the useless peptide, the good peptide and the bad peptide are like seeing flowers in the fog and looking at the moon in the water. For those experts who have the insight to know the truth, they can see the truth at a glance.

At present, there are thymosin, interferon, immunoglobulin and other peptide products in the world. They play a certain role in different historical stages, but they are not effective for modern virus and modern immunity. "Experts remind: blind use of thymosin is harmful and useless" in Guangming Daily pointed out: "some people buy a large number of Chinese herbal medicine, human immunoglobulin, interferon, thymosin, etc., hoping to prevent SARS by using drugs to improve the body's immunity. Their wishes are very good, but they often fail to achieve the expected goal. " At present, there are peptides produced by solid-phase method, liquid-phase method, microbial fermentation method, electrolysis method, acid hydrolysis method and alkali hydrolysis method in the world. These polypeptides have successively appeared in the historical stage of peptide research. However, with the development of science, most of the polypeptides produced by these methods are of high molecular weight, unstable molecular weight, complex process, large investment, few peptide and unstable peptide quality There are side effects. They have fallen behind in the face of scientific and technological innovation.

With the rapid development of science and technology, peptides, such as enzyme peptide, gene peptide and clone peptide, have emerged one after another, which are leading the trend of peptide industry and close to the international frontier of peptide science and technology. But at present, the most realistic peptide that can best reflect the level of modern science and technology is the enzyme peptide. Enzymatic polypeptide is a kind of high-purity protein which uses the separation technology of protein engineering to separate animal and plant proteins into high-purity proteins with protein content of more than 90%. Based on this, it uses the enzymolysis technology of bioengineering to enzymolysis and catalyze proteins. It is also the second high-tech deep processing product of food science. It is the crystallization of three scientific communication. Its scientific and technological content is different from that of general polypeptide Institute In comparison, there are many media reports during SARS.

"Five views" teaches you to recognize good peptides

Zou Yuandong, a famous expert in enzymatic peptide, taught us some simple and easy tips for peptide recognition

Peptide recognition depends on the size of its molecular weight segment. The compound of 2-9 amino acid chains connected by peptide bond is called small peptide. It has the highest value in all peptides, has strong activity and diversity, has important biological functions, can give full play to human physiological functions and enhance human physiological activities. It is an important physiological regulator. Therefore, when people choose peptide products, they should look at its molecular weight segment. Those with molecular weight segment below 1000 belong to small peptide. The peptides with molecular weight range of 1000-5000 belong to large peptides, which have different value compared with small peptides. Small peptides are more expensive than gold. But macropeptides are cheap.

Peptide recognition depends on its peptide content. The content of some peptide mixtures is very low, but the content of small peptide decomposed by protein isolate is particularly high, its energy and function are several times higher than the former.

To recognize peptide, we need to see how to make it. Some of the peptides produced by some methods not only have uneven molecular weight, but also contain chemical components. Some even have pollution. After eating, it is not only harmful to human health, but also harmful to human health. For example, the peptide produced by the decomposition of plant protein with plant protease is the best, and the peptide produced by the decomposition of animal protein with plant protease is also very beneficial to human body. The polypeptides produced by this method not only eliminate the allergens of animal and plant proteins, but also have no chemical residues, no bitterness and peculiar smell, unique flavor, fragrant smell, and identification peptide. It depends on whether it has the approval batch number of the Ministry of health, whether it has the national scientific research achievement appraisal or project approval and achievement certificate (because pseudoscience can not stand this pass).

To recognize a peptide, it depends on its formulation. The best dosage form of peptide products is aqueous oral liquid, which is absorbed faster than other dosage forms, has high utilization rate, easy storage, long shelf life and is not easy to pollute. Peptide synthesized by protein is a new weapon for human immune system.

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About Shengnuo

Chengdu Shengnuo Biotechnology Co., Ltd. has "Chengdu polypeptide drug engineering technology research center" in Chengdu, mainly engaged in polypeptide, polypeptide drug and beauty peptide research. Our zero defect has passed the FDA certification, and now it has become the first-class professional peptide drug and product development, technology transfer, technical service and peptide drug industry in the scale production and export of China's parks.