Immune diseases have been bothering many people's physical and mental health for many years. With the development of healthy China 2030, the mode of medical treatment has gradually changed from "disease-centered" to "patient-centered". In the field of tumor, liver disease and infection, immunotherapy has become another hot spot after traditional radiotherapy, chemotherapy and targeted therapy, and non-specific immunotherapy drugs have also attracted more and more attention.

Through the treatment and supplement of drugs, the body can generate a large number of "soldiers", enhance the phagocytosis of immune cells, make them more capable of killing bacteria, cancer cells, etc., to protect the health of the body.

At present, some immunodrugs have been approved in China. Immunomodulators such as thymopentin for injection are common clinical drugs.

Thymopentin is composed of five amino acids: arginine, lysine, aspartic acid, valine and tyrosine. It is an effective part of thymogenin II. Thymogenin II is a single peptide compound separated from thymic hormone, which is composed of 49 amino acids, and the peptide chain segment composed of 5 amino acids has the same physiological functions as thymogenin II, so it is called thymopentin.

Thymopentin for injection is produced by Chengdu shengnuo biopharmaceutical. Thymopentin for injection has a two-way regulatory effect on the immune function of the body. It can promote the maturation of T lymphocytes in the peripheral blood after mitogen activation, increase the secretion of T cells in various antigens or lymphokines (such as α, γ interferon, IL-2 and IL-3) after mitogen activation Add the level of lymphokine receptor on T cell.

At the same time, thymopentin for injection can enhance lymphocyte response by activating T4 helper cells. In addition, thymopentin for injection may affect the chemotaxis of NK precursor cells, which will become more cytotoxic after exposure to interferon.

Thymopentin for injection is suitable for chronic hepatitis B and various primary or secondary T-cell defects (such as children's congenital immunodeficiency). For some autoimmune diseases (such as rheumatoid arthritis, systemic lupus erythematosus, children's asthma and asthmatic bronchitis, etc.) and various diseases with low cellular immune function (such as viral hepatitis, prevention of upper respiratory tract infection, stubborn oral ulcer, etc.), it has an effect. It has adjuvant therapeutic effect on tumor.

And thymopentin has a significant characteristic. Although its half-life is short, only about 1 minute in vivo, it can cause immune regulation for a long time. Studies have shown that thymopentin can be rapidly degraded by protease and aminopeptidase in human plasma, with a half-life of about 30 seconds. However, the retention time in the abdominal cavity is longer than that in plasma, up to 3.5-7 minutes. After 10 minutes in saliva, 25% of thymopentin can not be degraded.

The special biological effect of thymopentin in the body makes the body not need to maintain a high plasma concentration of thymopentin, which can play the role of immune regulation. Therefore, in the treatment of long-term and chronic diseases, thymopentin is an effective adjuvant therapy.

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About Shengnuo

Chengdu Shengnuo Biotechnology Co., Ltd. has "Chengdu polypeptide drug engineering technology research center" in Chengdu, mainly engaged in polypeptide, polypeptide drug and beauty peptide research. Our zero defect has passed the FDA certification, and now it has become the first-class professional peptide drug and product development, technology transfer, technical service and peptide drug industry in the scale production and export of China's parks.