\1. Different meanings of Representatives:
(1) Peptide is a compound formed by α - amino acids linked together by peptide bond, which is the intermediate product of protein hydrolysis. The compound formed by dehydration and condensation of two amino acid molecules is called dipeptide. Similarly, there are three peptides, four peptides, five peptides, etc. Usually 10-100 amino acids are dehydrated and condensed into a compound called polypeptide.
(2) Peptide chain: every two amino acids are connected to form a peptide bond, and multiple amino acids are connected to form multiple peptide bonds. A chain structure containing multiple peptide bonds formed by multiple amino acids is called peptide chain.
\2. The number of amino acids contained is different:
(1) Usually 10-100 amino acids are dehydrated and condensed into a compound called polypeptide.
(2) The peptide chain includes dipeptides, tripeptides, etc., and also polypeptides.
Extended data
Types of polypeptides:
\1. Cytokine mimic peptide
The mimic peptides of many growth factors, such as human erythropoietin, human thrombopoietin, human growth hormone, human nerve growth factor and interleukin, have been screened abroad. The amino acid sequence of these mimic peptides is different from that of their corresponding cytokines, but they have the activity of cytokines and have the advantage of small molecular weight.
\2. Antibacterial active peptide
When insects are stimulated by the external environment, they produce a large number of cationic peptides with antibacterial activity. More than 100 kinds of antimicrobial peptides have been screened out. In vitro and in vivo experiments have proved that many antimicrobial peptides not only have strong bactericidal ability but also kill tumor cells.
\3. Peptides for cardiovascular diseases
\4. Many plant traditional Chinese medicines have the functions of lowering blood pressure, blood lipid and hemolytic thrombus, which can not only be used as medicine, but also as health food.
\5. Other small medicinal peptides
Small peptide drugs have made great progress in these aspects, but also in many other areas. For example, Stiernberg found that a synthetic peptide peptide can promote the regeneration of wound blood vessels and accelerate the healing of deep wounds. Carron et al. Confirmed that the two synthetic peptides screened could inhibit the resorption of osteoclasts to bone.
\6. Diagnostic polypeptide
The main use of polypeptides in diagnostic reagents is to detect antibodies against viruses, cells, mycoplasma, spirochetes and cysticercosis, trypanosomes and other parasites. Polypeptides are more specific than natural microorganisms or parasite protein antigens, and are easy to prepare. Therefore, the false negative rate and background reaction of the assembled detection reagents are very low, which are easy to be used in clinic Use.
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About Shengnuo
Chengdu Shengnuo Biotechnology Co., Ltd. has "Chengdu polypeptide drug engineering technology research center" in Chengdu, mainly engaged in polypeptide, polypeptide drug and beauty peptide research. Our zero defect has passed the FDA certification, and now it has become the first-class professional peptide drug and product development, technology transfer, technical service and peptide drug industry in the scale production and export of China's parks.